A Plague Tale: Requiem is set in the South of France in the 14th century’s Europe during the plague pandemic. It is the continuation of A Plague Tale Innocence that features its protagonists Amicia, her brother Hugo as well as Beatrice and Lucas. Amicia is trying to find a cure for her sick brother who’s condition worsens with every stressful situation he endures. Her situation is even more difficult because of Hugos’ unique abilities. She has to deal with taking unpredictable turns events.
We never know what will happen next. A Plague Tale allows us to experience all the horrors of the pandemic with a vivid depiction of plague effects.

Amicia and Hugo have to fight the plague, defeat opponents and manage to survive amidst death and destruction caused by this plague as well as war. They have to solve puzzles while battling enemies. She also has to defeat various supernatural forces. For physical damage, she uses weapons such as a knife and cross-bow. These weapons can be enhanced with tools such as fire, saltpeter, or tar. Each enemy has to be defeated differently. We also need to be inventing how we use various tools to battle opponents that need to be kept at a distance as well as unblock our path. Our path choice can be freely chosen.

A Plague Tale: Requiem has graphic depictions involving both beautiful scenes as well as corpses or other visually shocking aspects of life in these times. The game incorporates elements of battles with elements of stealth that prevail.